GENOMIC ARRAYS IDENTIFY HIGH-RISK CHRONIC LYMPHOCYTIC LEUKEMIA WITH GENOMIC COMPLEXITY: A MULTI-CENTER STUDY

Alexander C Leeksma, Panagiotis Baliakas, Theodoros Moysiadis, Anna Puiggros, Karla Plevova, Anne-Marie van der Kevie-Kersemaekers, Hidde Posthuma, Ana E Rodriguez-Vicente, Anh Nhi Tran, Gisela Barbany, Larry Mansouri, Rebeqa Gunnarsson, Helen Parker, Eva van den Berg, Mar Bellido, Zadie Davis, Meaghan Wall, Ilaria Scarpelli, Anders Österborg, Lotta Hansson, Marie Jarosova, Paolo Ghia, Pino Poddighe, Blanca Espinet, Sarka Pospisilova, Constantine Tam, Loïc Ysebaert, Florence Nguyen-Khac, David Oscier, Claudia Haferlach, Jacqueline Schoumans, Marian Stevens-Kroef , Eric Eldering, Kostas Stamatopoulos, Richard Rosenquist, Jonathan C Strefford, Clemens Mellink, Arnon P Kater.

Haematologica, 2020 Jan 23

FRONTLINE TREATMENT WITH THE COMBINATION OBINUTUZUMAB ± CHLORAMBUCIL FOR CHRONIC LYMPHOCYTIC LEUKEMIA OUTSIDE CLINICAL TRIALS: RESULTS OF A MULTINATIONAL, MULTICENTER STUDY BY ERIC AND THE ISRAELI CLL STUDY GROUP

Yair Herishanu; Adir Shaulov; Riva Fineman; Sandra Bašić‐Kinda; Ariel Aviv; Ewa Wasik‐Szczepanek; Ozren Jaksic; Mihnea Zdrenghea; Uri Greenbaum; Inga Mandac; Martin Simkovic; Marta Morawska; Ohad Benjamini; Martin Spacek; Anatoly Nemets; Osnat Bairey; Livio Trentin; Rosa Ruchlemer; Luca Laurenti; Oana Stanca Ciocan; Michael Doubek; Lev Shvidel; Nagib Dali; Fátima Mirás; Anne De Meûter; Maria Dimou; Francesca R. Mauro; Marta Coscia; Horia Bumbea; Róbert Szász; Tamar Tadmor; Odit Gutwein; Massimo Gentile; Lydia Scarfò; Alessandra Tedeschi; Paolo Sportoletti; Eva Gimeno Vázquez; Juan Marquet; Sarit Assouline; Maria Papaioannou; Andrei Braester; Luciano Levato; Michael Gregor; Gian M. Rigolin; Javier Loscertales; Angeles Medina Perez; Marten R. Nijziel; Viola M. Popov; Rosa Collado; Irma Slavutsky; Gilad Itchaki; Shimrit Ringelstein; Neta Goldschmidt; Chava Perry; Shai Levi; Aaron Polliack; Paolo Ghia

AJH_2020_Feb_25._doi/abs/10.1002/ajh.25766

COMPARATIVE ANALYSIS OF TARGETED NEXT-GENERATION SEQUENCING PANELS FOR THE DETECTION OF GENE MUTATIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA: AN ERIC MULTI-CENTER STUDY

Lesley-Ann Sutton, Viktor Ljungström, Anna Enjuanes, Diego Cortese, Aron Skaftason, Eugen Tausch, Katerina Stano Kozubik, Ferran Nadeu, Marine Armand, Jikta Malcikova, Tatjana Pandzic, Jade Forster, Zadie Davis, David Oscier, Davide Rossi, Paolo Ghia, Jonathan C Strefford, Sarka Pospisilova, Stephan Stilgenbauer, Frederic Davi, Elias Campo, Kostas Stamatopoulos, Richard Rosenquist, European Research Initiative on CLL (ERIC).

Haematologica 2020 Apr 9

IMMONUGLOBULIN GENE ANALYSIS IN CHRONIC LYMPHOCYTIC LEUKEMIA IN THE ERA OF NEXT GENERATION SEQUENCING

Davi F, Langerak AW, de Septenville AL, Kolijn PM, Hengeveld PJ, Chatzidimitriou A, Bonfiglio S, Sutton LA, Rosenquist R, Ghia P, Stamatopoulos K; ERIC, the European Research Initiative on CLL, and the EuroClonality-NGS Working Group. Leukemia. 2020 Jun 19. doi: 10.1038/s41375-020-0923-9.

Leukemia . 2020 Jun 19. doi: 10.1038/s41375-020-0923-9

COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus

Lydia Scarfò, Thomas Chatzikonstantinou, Gian Matteo Rigolin, Giulia Quaresmini, Marina Motta, Candida Vitale, Jose Antonio Garcia-Marco, José Ángel Hernández-Rivas, Fatima Mirás, Mónica Baile, Juan Marquet, Carsten U. Niemann, Gianluigi Reda, Talha Munir, Eva Gimeno, Monia Marchetti, Francesca Maria Quaglia, Marzia Varettoni, Julio Delgado, Sunil Iyengar, Ann Janssens, Roberto Marasca, Angela Ferrari, Carolina Cuéllar-García, Gilad Itchaki, Martin Špaček, Lorenzo De Paoli, Luca Laurenti, Mark-David Levin, Enrico Lista, Francesca R. Mauro, Martin Šimkovič, Ellen Van Der Spek, Elisabeth Vandenberghe, Livio Trentin, Ewa Wasik- Szczepanek, Rosa Ruchlemer, Dominique Bron, Maria Rosaria De Paolis, Giovanni Del Poeta, Lucia Farina, Myriam Foglietta, Massimo Gentile, Yair Herishanu, Tobias Herold, Ozren Jaksic, Arnon P. Kater, Sabina Kersting, Lara Malerba, Lorella Orsucci, Viola Maria Popov, Paolo Sportoletti, Mohamed Yassin, Barbara Pocali, Gabor Barna, Annalisa Chiarenza, Gimena dos Santos, Eugene Nikitin, Martin Andres, Maria Dimou, Michael Doubek, Alicia Enrico, Yervand Hakobyan, Olga Kalashnikova, Macarena Ortiz Pareja, Maria Papaioannou, Davide Rossi, Nimish Shah, Amit Shrestha, Oana Stanca, Niki Stavroyianni, Vladimir Strugov, Constantine Tam, Mihnea Zdrenghea, Marta Coscia, Kostas Stamatopoulos, Giuseppe Rossi, Alessandro Rambaldi, Emili’ Montserrat, Robin Foà, Antonio Cuneo, Paolo Ghia 

Leukemia . 2020 Jul 9;1-10. doi: 10.1038/s41375-020-0959-x

Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL

Andreas Agathangelidis (Centre for Research and Technology Hellas, Greece); Anastasia Chatzidimitriou (Karolinska Institute, Sweden); Katerina Gemenetzi (Democritus University of Thrace, Greece); Veronique Giudicelli (IMGT, France) Maria Karypidou (Centre for Research and Technology Hellas, Greece); Karla Plevova (Masaryk University, Czech Republic); Zadie Davis (Royal Bournemouth Hospital, United Kingdom); Xiao-Jie Yan (Feinstein Institute for Medical Research, Northwell Health, United States) Sabine Jeromin (MLL GmbH, Germany) Christof Schneider (University Hospital Medical Center, Germany); Lone Pedersen (Rigshospitalet, Denmark); Renee Tschumper (Mayo Clinic College of Medicine, United States); Lesley Sutton (Karolinska Institutet, ); Panagiotis Baliakas (Science for Life Laboratory, Uppsala University, Sweden); Lydia Scarfò (Laboratory of B cell Neoplasia, Division of Experimental Oncology, Istituto Scientifico San Raffaele, Italy); Ellen van Gastel (Erasmus MC, University Medical Center, Netherlands); Marine Armand (Sorbonne Université, UMR_S 1138, Centre de Recherche des Cordeliers, France); Eugen Tausch (Ulm University, Germany); Bella Biderman (National Research Center for Hematology, Russian Federation); Constance Baer (Munich Leukemia Laboratory, Germany); Davide Bagnara (University of Genova, Italy) Alba Navarro (Institut d’Investigacions Biomediques August Pi I Sunyer, Spain); Anne de Septenville (Sorbonne Université, UMR_S 1138, Centre de Recherche des Cordeliers, France); Valentina Guido (Niguarda Cancer Center, Niguarda Hospital, Italy) Gerlinde Mitterbauer-Hohendanner (Medical University of Vienna, Austria); Aleksandar Dimovski (University Ss Cyril and Methodius, Macedonia, Republic of); Christian Brieghel (Copenhagen University, Rigshospitalet, Denmark); Sarah Lawless (Belfast City Hospital, Belfast Health and Social Care Trust, United Kingdom) Manja Meggendorfer (MLL, Germany); Kamila Stranska (Masaryk University, Czech Republic); Matthias Ritgen (University Clinic of Schleswig-Holstein, Kiel, Germany); Monica Facco (Veneto Institute of Molecular Medicine, Italy) Cristina Tresoldi (ospedale San Raffaele, Italy) Andrea Visentin (Veneto Institute of Molecular Medicine, Italy); Andrea Patriarca (Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Italy); Mark Catherwood (Belfast City Hospital, United Kingdom) Lisa Bonello (CeRMS, Italy) Andrey Sudarikov (National Research Center for Hematology, Russian Federation); Katrina Vanura (Medical University of Vienna, Austria); Maria Roumelioti (1st Department of Propedeutics, University of Athens, Laikon General Hospital, Athens, Greece, Greece) Hana Skuhrova Francova (University Hospital Brno, Masaryk University,; Theodoros Moysiadis (Centre for reasearch and Technology Hellas); Silvio Veronese (Azienda Ospedaliera Ospedale Niguarda Ca’ Granda, Italy); Krzysztof Giannopoulos (Medical University of Lublin, Poland) Larry Mansouri (Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden, Sweden); Teodora Karan-Djurasevic (Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Serbia); Raphael Sandaltzopoulos (Department of Molecular Biology and Genetics, Democritus University of Thrace, Greece); Csaba Bödör (Institute of Cancer, United Kingdom); Franco Fais (U.O. Molecular Pathology, IRCCS Ospedale Policlinico San Martino, Italy); Arnon Kater (Dept Hematology, Cancer Center Amsterdam, Amsterdam, University of Amsterdam, Netherlands); Irina Panovska-Stavridis (University Clinic of Hematology-Skopje, Macedonia (The Former Yugoslav Republic); Davide Rossi (Oncology Institute of Southern Switzerland, Switzerland); Salem Alshemmari (Faculty of Medicine, Kuwait University, Kuwait) Panagiotis Panagiotidis (University of Athens Medical School, Greece); Paul Costeas (The Center for the Study of Haematological Malignancies, Cyprus); Blanca Espinet (Hospital del Mar, Spain); Darko Antic (Clinic for hematology, Clinical Center Serbia, Serbia); Letizia Foroni (Imperial College Hammersmith Campus, United Kingdom); Marco Montillo (Niguarda Cancer Center, Niguarda Hospital, Italy); Livio Trentin (Veneto Institute of Molecular Medicine, Italy); Niki Stavroyianni (G. Papanicolaou Hospital, Greece); Gianluca Gaidano (University of Eastern Piedmont, Italy) Paola Francia di Celle (AO Città della Salute e della Scienza, Italy); Carsten Niemann (Rigshospitalet, Denmark); Elías Campo (Institut d’Investigacions Biomediques August Pi I Sunyer, Spain); Achilles Anagnostopoulos (George Papanicolaou Hospital, Greece) Christiane Pott (University Hospital Schleswig-Holstein, Germany); Kirsten Fischer (University Hospital Cologne, Germany); Michael Hallek (University of Cologne, Germany) David Oscier (Royal Bournemouth Hospital, United Kingdom); Stephan Stilgenbauer (University of Ulm, Germany) Claudia Haferlach (MLL Munich Leukemia Laboratory, Germany); Diane Jelinek (Mayo Clinic, United States); Nicholas Chiorazzi (The Feinstein Institute for Medical Research, United States); Sarka Pospisilova (Central European Institute of Technology (CEITEC), Masaryk University, Czech Republic); Marie-Paule Lefranc (IMGT®, the international ImMunoGeneTics information system®, Laboratoire d’ImmunoGénétique Moléculaire (LIGM); Institut de Génétique Moléculaire (IGH); CNRS, Université de Montpellier (UM), France); Sofia Kossida (IMGT, IGH, CNRS, University of Montpellier, France); Anton Langerak (Erasmus MC, Netherlands); Chrysoula Belessi (General Hospital of Nikea, Greece); Frederic DAVI (Department of Hematology, AP-HP La Pitie- Salpetriere, Paris, FR, France); Richard Rosenquist (Clinical Genetics, Karolinska University Laboratory, Karolinska University Hospital, Sweden); Paolo Ghia (Università Vita-Salute San Raffaele C.F 97187560152, Italy); Kostas Stamatopoulos (Institute of Applied Biosciences, Centre for Research and Technology

BLD-2020-007039R1

Challenges and Solutions for Collecting and Analyzing Real World Data: The Eric CLL Database as an Illustrative Example

Anastasia Chatzidimitriou; Eva Minga; Thomas Chatzikonstantinou; Carol Moreno; Kostas Stamatopoulos; Paolo Ghia, Paolo; on behalf of ERIC, the European Research Initiative on CLL

HemaSphere: October 2020 – Volume 4 – Issue 5 – p e425