ERIC | IgCLL Workshop 2007 | Downloads

Sequences

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Session I – CLL and immunoglobulin genes Chair: Richard Rosenquist
09:00	Welcome, introduction	Richard Rosenquist
09:15	Immunogenetics – clues to the origin and behaviour of B-cell malignancies	Freda Stevenson
09:50	Somatic hypermutation as a prognostic marker in CLL - relationship to other prognostic markers	Paolo Ghia
10:15	ERIC recommendations on Ig gene analysis in CLL	Richard Rosenquist
11:00	New prognostic markers in a clinical perspective	Eva Kimby
Session II – Interpretation of clonality (tutorial)
11:30	Organization of immunoglobulin genes	Frédéric Davi
	Selection of primers and PCR conditions, how to interpret clonality using different detection methods	Frédéric Davi
Session III – Interpretation of Ig sequences and database searches (tutorial)
13:30	Interpretation of Ig gene sequences	Marie-Paule Lefranc
14:00	Basic exercises I	Frédéric Davi
16:00	Immunoglobulin gene databases and online resources	Marie-Paule Lefranc

Session IV – Interpretation of 'trouble sequences' (tutorial)
08:30	Introduction to ‘trouble sequences’	Chrysoula Belessi
Session V – Ig gene analysis in clinical routine (tutorial)
13:00	How to report Ig gene data in clinical routine?	Richard Rosenquist
13:30	Cases difficult to categorize	Kostas Stamatopoulos
Session VI – Stereotyped B-cell receptors in CLL Chair: Paolo Ghia
14:00	Restricted IGHV gene usage and homologous CDR3s in CLL	Gerard Tobin
14:25	Biological and clinical features of stereotyped B-cell receptors in CLL	Kostas Stamatopoulos

15:25	Concluding remarks	Paolo Ghia